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Each capsule contains
Zanamivir…5 mg

Treatment of Influenza
VIRENZA is indicated for treatment of uncomplicated acute illness due to influenza A and B virus in adults and pediatric patients 7 years and older that has been symptomatic for no more than 2 days.

Prophylaxis of Influenza
VIRENZA is indicated in adults and pediatric patients 5 years of age and older for prophylaxis of influenza.

VIRENZA is not recommended for treatment of patients with underlying airways disease (such as asthma or chronic obstructive pulmonary disease)

VIRENZA is for administration to the respiratory tract by oral inhalation using Revolizer device only.

Patients scheduled to use an inhaled bronchodilator at the same time as VIRENZA should use their bronchodilator before taking VIRENZA.

Treatment of Influenza
The recommended dose of VIRENZA for treatment of influenza in adults and pediatric patients aged 7 years and older is 2 inhalations (one 5-mg capsule per inhalation for a total dose of 10 mg) twice daily (approximately 12 hours apart) for 5 days.

Two doses should be taken on the first day of treatment whenever possible provided there is at least 2 hours between doses. On subsequent days, doses should be about 12 hours apart (e.g., morning and evening) at approximately the same time each day. There are no data on the effectiveness of treatment with Zanamivir when initiated more than 2 days after the onset of signs or symptoms.

Prophylaxis of Influenza
Household Setting: The recommended dose of VIRENZA for prophylaxis of influenza in adults and pediatric patients 5 years of age and older in a household setting is 10 mg once daily for 10 days. The 10-mg dose is provided by 2 inhalations (one 5-mg blister per inhalation). The dose should be administered at approximately the same time each day. There are no data on the effectiveness of prophylaxis with VIRENZA in a household setting when initiated more than 1.5 days after the onset of signs or symptoms in the index case.

Community Outbreaks: The recommended dose of VIRENZA for prophylaxis of influenza in adults and adolescents in a community setting is 10 mg once daily for 28 days. The 10-mg dose is provided by 2 inhalations (one 5-mg blister per inhalation). The dose should be administered at approximately the same time each day. There are no data on the effectiveness of prophylaxis with VIRENZA in a community outbreak when initiated more than 5 days after the outbreak was identified in the community. The safety and effectiveness of prophylaxis withVIRENZA have not been evaluated for longer than 28 days duration.

VIRENZA is contraindicated in patients with a known hypersensitivity to any component of the formulation

VIRENZA is available in a container with 20 capsules and the Revolizer.